Microbiome Bites September 25th

Obese microbiome | ThinkBiome

It seems we’re thinking about the children in microbiome research this week.
1. Scientists Are Now Trying Fecal Transplants on Kids
Fecal microbiota transplants (FMT) have shown great promise in treating recurrent C. difficile infections. Now scientists in Ontario have set up a clinical trial to test FMT as a treatment for Inflammatory Bowel Disease (IBD) in children. Prior research by the group has shown promise for the treatment in adults, so there’s good reason to be hopeful that this will work in children. Read more here.
2. Obese Kids Have Different Germs in Their Gut
Children and teenagers who are obese have different microorganisms living in the digestive tract than their lean counterparts, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. The researchers identified eight groups of gut bacteria that were linked to the amount of fat in the body. Four of them thrived more in the obese youngsters. Read more here.

3. Prebiotic Effects of Xylooligosaccharides on the Improvement of Microbiota Balance in Human Subjects
Prebiotics are a good way to get the most out of probiotics. Prebiotics are a type of soluble fiber that can be consumed and fermented by our gut flora. There are a few types of prebiotics including inulin and oligofructose, along with fructooligosaccharides (FOS), galactooligosaccharides (GOS), and other oligosaccharides.
In a study published this week in the journal Gastroenterology and Research Practice, scientists show that consumption of prebiotic xylooligosaccharides- (XOS-) enriched rice porridge significantly improves the intestinal microbiota balance over a 6-week period. You can read the study here.

4. The Microbiome Project: Probiotics
Here is a nice short video on the health benefits of commercial and clinical probiotics presented by Dr. Jack Gilbert with help from Julie Bubeck Wardenburg from the University of Chicago and Susan Erdman from MIT.